Bioinformatics Solutions

Bringing Clarity to Complexity

Signios Bio leverages AI and machine learning (ML) models for managing and analyzing vast and complex data sets generated by modern omics technologies and next-generation sequencing.This approach provides a powerful foundation for advancing omics research, from variant discovery to facilitating identification of novel biomarkers and driving enhanced disease insights.

Data Analysis for Omics Data

Our bioinformatics expertise is a cornerstone of our sequencing services and tailored to each method—from whole genome and RNA sequencing to TCR, BCR, single-cell, and spatial analyses. Our pipelines not only manage vast amounts of data, but also delivers actionable biological insights, presenting results through integrative, publication-ready visualizations and tables. Embedded within a proprietary reporting platform, Mango, our bioinformatics approach ensures that every analysis yields meaningful and accessible insights for researchers.

True Multiomics Integration

We offer researchers a variety of solutions to study specific areas —such as RNA-seq, exome, whole genome, and single-cell sequencing. Our true multiomics pipeline, Multiome Signal, overcomes the limitations of traditional analytics by seamlessly integrating data from multiple assays, delivering unbiased, unsupervised insights. This approach applies across fields, from drug discovery, where treatment response data can be analyzed alongside gene expression and patient outcomes, to cancer research, enabling detailed exploration of cancer subtypes and cell states for a more precise understanding of disease biology.

Pipeline and Report Development for Diagnostics and Companion Diagnostics

Our customizable NGS pipeline and reporting solutions meet the needs of diagnostics and companion diagnostics developers. With specialized panels, including oncology-specific options and broader exome sequencing, we provide targeted insights that reveal underlying conditions and cancer-specific biomarkers. Tailored pipelines enable precise data interpretation for patient subgroups, facilitating discovery of gene markers uniquely associated with specific disease models or cancer related tumor infiltrating immune cells. Additionally, we offer customizable bioinformatics platforms for biotech and pharma partners, allowing them to visualize, investigate, and analyze their own data securely on-site. This empowers researchers to ask and answer specific biological questions independently, leveraging a comprehensive toolset for diagnostics and data exploration.

The Signios Difference for Analysis

Automated Pipelines

Automated Pipelines

Fast, reliable, and reproducible data processing minimizes turnaround times, allowing you to focus on your research.

Integrated Multiomics Tools

Multiomics Tools

Seamlessly integrate genomic, transcriptomic, and proteomic data for a comprehensive view of complex biological systems.

Scalable Infrastructure

Scalable Infrastructure

Handle projects of any size, from single-sample studies to high-throughput datasets, supporting diverse research needs.

Expert-Led Analysis

Expert-Led Analysis

PhD-level bioinformatics scientists ensure that raw data translates into actionable insights for impactful research.

Customizable Outputs

Customizable Outputs

Deliver interactive reports and publication-ready figures tailored to your needs for high-quality presentations and publications.

Inclusive Insights

Inclusive Insights

Leverage MedGenome-powered access to underrepresented populations to enrich research and support diverse studies.