Multiomics Service Provider for Genomics and Proteomics Research
Scientist-led next-gen sequencing (NGS) services designed to support research from project design through data analysis.
Our Sequencing Services
Signios is a genomics and proteomics service provider delivering end-to-end next-generation sequencing (NGS) and multiomics services. Our San Francisco Bay Area lab in Foster City, California supports academic, biotechnology, and biopharma research teams with integrated bioinformatics and high-quality sequencing services.
Sequencing and multiomics solutions to drive discovery in genetic disease research.
Sequencing, multiomics, antibody engineering, and real-world evidence to improve discovery & development.
Leverage real-world evidence (RWE) from global research networks across the US, Europe, Asia, Africa, Middle East, and Latin America.
Infrastructure and expertise for partners to develop, validate, and distribute Dx and CDx.
Complement your operations with Lab-in-the-cloud (LINC) modular dry-lab services
Enhanced capabilities with advanced multiomics insights, robust data resources, and streamlined workflows.
Scientist-Led Multiomics Excellence
From study design to data interpretation in our San Francisco Bay Area lab in Foster City, California, our scientist-led approach ensures every step is aligned to deliver reliable, actionable insights.
Scientist-Led Study Design
PhD scientists guide experimental design, platform selection, and biological interpretation—ensuring every study produces meaningful insights.
Multi-Omics Platform Expertise
Validated workflows across 10x Genomics, Olink, Twist, Illumina, and PacBio, enabling the right technology for every research question.
In-House Laboratory Execution
All sequencing workflows run in our Foster City laboratory, ensuring full quality control, operational consistency, and faster turnaround.
Integrated Bioinformatics
Automated pipelines transform raw sequencing data into structured, biologically relevant insights aligned with your study objectives.
Unified Data-to-Insight Workflow
Sequencing and bioinformatics teams operate within integrated workflows—from sample processing to biological interpretation.
Advancing Research Accross Therapeutic Areas
Signios Bio supports research across diverse therapeutic areas and complex diseases integrating multi-omic services from bulk, single cell, spatial and proteomics applications advancing discovery for disease biology, translational research, biomarker discovery and precision medicine groups.
Oncology
Sequencing capabilities allow for in-depth investigation into tumor genomics, tumor microenvironments, and molecular pathways driving cancer progression
Immunology
Rare Diseases
Whole genome and exome sequencing to enable discovery of novel genetic mutations and understanding the genetic basis of rare disorders
Neurology Disorders
RWE supports epidemiological studies, population health research, and the development of inclusive therapies that address global health disparities
Pharmagenomics & Precision Medicine
Certified Platform Expertise
Signios Bio is led by scientists who understand experimental design, molecular biology, and downstream analysis. We engage early in study planning and remain involved through data delivery to ensure scientific rigor at every stage.
We are certified service providers across leading sequencing and proteomic platforms, including Illumina, 10x Genomics, PacBio, Olink, and Twist Bioscience. All workflows are executed in-house in our Foster City, California, laboratory using validated protocols and quality-controlled processes.
Signios By the Numbers
200+
peer-reviewed publications
1,000+
citations of our work
DNA sequencing assays run
single-cells sequenced
17M+
Unique variants identified
250,000+
transcriptomes sequenced
Trusted by Leading Academic and Biopharma Research Organizations
Many of the world’s leading academic and biopharmaceutical companies partner with Signios Bio to unlock deeper insights into the biology of disease and enable the future of precision medicine.
What research leaders say about Signios?
Our Customers
Many of the world’s leading academic and biopharmaceutical companies partner with Signios Bio to unlock deeper insights into the biology of disease and enable the future of precision medicine.
Here are just a few.
Diverse, multimodal omics data is the path to make the next breakthroughs in drug discovery & precision medicine
+70%
Multiomics integration increases biomarker discovery success rates by 70%
2.6x
Drug targets with genetic support are 2.6 times more likely to succeed in clinical trials
-25%
Effective use of genomics and bioinformatics in drug development can reduce R&D costs by up to 25%
Leveraging cutting-edge multiomics technologies, advanced bioinformatics, and AI-driven insights, we transform complex biological data into actionable breakthroughs that accelerate drug development, diagnostics, and precision medicine
Our
Science
Our Capabilities
Signios Bio is a leading sequencing service provider based in Foster City, California, offering a wide range of gene and genome sequencing capabilities. Services include whole genome sequencing (WGS), whole exome sequencing (WES), immune repertoire sequencing, epigenomics, and long-read sequencing.
The Foster City laboratory is equipped with high-throughput platforms such as the Illumina NovaSeq X Plus, MiSeq, PacBio Revio, 10X Genomics Chromium, Visium Spatial, and the Sony MA900 Cell Sorter—supporting complex research applications across multiple domains.
Signios Bio also specializes in RNA-Seq, single-cell and spatial transcriptomics, and provides comprehensive bioinformatics analysis with every project. From data processing to customized reporting, the in-house team ensures accurate, actionable results.
Whether you’re looking for NGS sequencing services in the Bay Area or anywhere in the U.S., Signios Bio delivers the technology, expertise, and turnaround times needed to support complex research.
The latest from Signios
April 17 – 22, 2026
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NEWS
Meet our team at AACR Booth #3444 and explore our advanced multiomics solutions.
April 10, 2025
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Press Release
Signios Bio Launches with AI-Driven Bioinformatics Platform and Multiomics Expertise to Advance Precision Medicine
April 10, 2025
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NEWS
Global Health Council recognizes Signios Bio as a Health Hero in docuseries by same name
Ready to Start Your Sequencing Project?
Partner with a scientist-led team delivering genomics, single-cell, spatial, and proteomics services with integrated bioinformatics support.