Multiomics Service Provider for Genomics and Proteomics Research
Scientist-led NGS and multiomics services from our Foster City, CA (SF Bay Area) lab, supporting research teams across the United States. We offer fully customizable, end-to-end solutions—from guided project design to expert data analysis—tailored to your unique sample requirements and research goals.
End-to-End Multiomics & NGS Sequencing Services
Signios Bio is a premier multiomics service provider built on the principle of expert partnership. Utilizing gold-standard, industry-leading technologies, our scientist-led team provides the flexibility researchers need through highly customizable workflows that adapt to complex sample variations. Based in the San Francisco Bay Area and serving the broader US, we combine competitive pricing and flexible turnaround times with high-level technical guidance. Whether you require a fully hands-on collaborative design or a streamlined, hands-off sequencing partner, we deliver the end-to-end NGS and bioinformatics support necessary to drive your next breakthrough.
Sequencing and multiomics services to drive discovery in genetic disease research.
Sequencing and multiomics solutions to drive discovery in genetic disease research.
Sequencing and multiomics solutions to drive discovery in genetic disease research.
Sequencing, multiomics, antibody engineering, and real-world evidence to improve discovery & development.
Leverage real-world evidence (RWE) from global research networks across the US, Europe, Asia, Africa, Middle East, and Latin America.
Infrastructure and expertise for partners to develop, validate, and distribute Dx and CDx.
Complement your operations with Lab-in-the-cloud (LINC) modular dry-lab services
Enhanced capabilities with advanced multiomics insights, robust data resources, and streamlined workflows.
Scientist-Led Multiomics Excellence
Signios Bio combines advanced technical infrastructure with deep biological expertise to redefine multi-omic research. Operating out of our state-of-the-art Foster City lab, our PhD-level scientists oversee every touchpoint of the process, ensuring rigorous quality control from the first library preparation to the final bioinformatics report. This hands-on, scientist-to-scientist collaboration guarantees that your data is not only accurate but truly actionable for translational research and early-stage drug discovery.
Scientist-Led Study Design
PhD scientists guide experimental design, service selection, and biological interpretation—ensuring every study produces meaningful insights.
Multi-Omics Platform Expertise
Validated workflows across 10x Genomics, Olink, Twist, Illumina, and PacBio, enable the right technology for every research questions.
In-House Laboratory Execution
All sequencing services run in our Foster City laboratory, ensuring full quality control, operational consistency, and fast delivery timelines.
Unified Data-to-Insight Workflow
Sequencing and bioinformatics teams operate within integrated workflows—from sample processing to biological interpretation.
Integrated Bioinformatics
Automated pipelines transform raw sequencing data into structured, biologically relevant insights aligned with your study objectives.
Advancing Research Across Therapeutic Areas
Signios Bio serves as an expert extension of your research team, helping navigate the complexities of modern disease biology. By uniting diverse multi-omic technologies—including bulk sequencing, single-cell analysis, spatial transcriptomics, and proteomics—under one roof, we provide the high-resolution data required to drive innovation. Our scientist-led workflows empower translational research and biomarker discovery teams to transform molecular insights into the next generation of precision therapies.
Oncology
From decoding complex tumor genomics to characterizing immune infiltration, our multi-omic workflows answer the toughest questions in cancer biology. We provide deep insights into the pathways driving progression, helping researchers validate targets and accelerate the development of precision therapies.
Immunology
From TCR/BCR sequencing to single-cell profiling, we provide a holistic view of the immune landscape. Our multi-omic approach enables researchers to dissect immune activation and exhaustion, uncovering the biomarkers and mechanisms behind autoimmune and inflammatory diseases.
Rare Diseases
Identify the molecular drivers of undiagnosed conditions with high-resolution Whole Genome and Exome Sequencing. We provide the deep genomic coverage required to uncover novel mutations and clarify the genetic basis of rare disorders, helping researchers accelerate the path to diagnosis and therapeutic development.
Neurology Disorders
Map the molecular architecture of the brain with spatial biology and single-cell sequencing. We help researchers decode the cellular heterogeneity of neurodegenerative disorders, identifying the localized biomarkers and therapeutic targets necessary to understand disease progression and neuroinflammation.
Metabolic & Cardiovascular Disorders
Identify the molecular drivers of metabolic and cardiovascular disease through high-sensitivity proteomics and genomic profiling. Our validated workflows help researchers uncover critical biomarkers for insulin resistance, obesity, and atherosclerosis, providing the foundational insights required to advance precision therapies for metabolic health.
Cell & Gene Therapy (CGT)
Optimize the development of advanced therapeutics with high-resolution molecular characterization. Our single-cell and long-read sequencing services enable precise monitoring of gene editing outcomes, CAR-T cell persistence, and vector integration, providing the essential data needed to ensure the safety and efficacy of next-generation biologics.
Certified Platform Expertise
Signios Bio is a scientist-led NGS and proteomics service provider dedicated to experimental rigor and molecular insight. From initial study design to advanced bioinformatics, our PhD-level experts ensure every project is optimized for high-quality data delivery.
As a Certified Service Provider for 10x Genomics, Takara, Olink, Illumina, PacBio, and Twist Bioscience, we execute all workflows in-house at our Foster City, CA (SF Bay Area) laboratory. Our validated protocols and quality-controlled processes guarantee consistent, reproducible results for every study.
Signios By the Numbers
200+
peer-reviewed publications
1,000+
citations of our work
DNA sequencing assays run
single-cells sequenced
17M+
Unique variants identified
250,000+
transcriptomes sequenced
Trusted by Leading Academic and Biopharma Research Organizations
At Signios Bio, we don’t just provide services; we build scientific alliances. Many of the world’s most influential biopharmaceutical and academic organizations rely on our multiomics expertise to drive their biomarker and translational programs. Together, we are accelerating the pace of innovation and setting a new standard for precision medicine in the U.S. and beyond.
What research leaders say about Signios?
Our Customers
Many of the world’s leading academic and biopharmaceutical companies partner with Signios Bio to unlock deeper insights into the biology of disease and enable the future of precision medicine.
Here are just a few.
Diverse, multimodal omics data is the path to make the next breakthroughs in drug discovery & precision medicine
+70%
Multiomics integration increases biomarker discovery success rates by 70%
2.6x
Drug targets with genetic support are 2.6 times more likely to succeed in clinical trials
-25%
Effective use of genomics and bioinformatics in drug development can reduce R&D costs by up to 25%
Leveraging cutting-edge multiomics technologies, advanced bioinformatics, and AI-driven insights, we transform complex biological data into actionable breakthroughs that accelerate drug development, diagnostics, and precision medicine
Our
Science
Our Capabilities
Signios Bio is a leading sequencing service provider based in Foster City, California, offering a wide range of gene and genome sequencing capabilities. Services include whole genome sequencing (WGS), whole exome sequencing (WES), immune repertoire sequencing, epigenomics, and long-read sequencing.
The Foster City laboratory is equipped with high-throughput platforms such as the Illumina NovaSeq X Plus, MiSeq, PacBio Revio, 10X Genomics Chromium, Visium Spatial, and the Sony MA900 Cell Sorter—supporting complex research applications across multiple domains.
Signios Bio also specializes in RNA-Seq, single-cell and spatial transcriptomics, and provides comprehensive bioinformatics analysis with every project. From data processing to customized reporting, the in-house team ensures accurate, actionable results.
Whether you’re looking for NGS sequencing services in the Bay Area or anywhere in the U.S., Signios Bio delivers the technology, expertise, and turnaround times needed to support complex research.
The latest from Signios
April 17 – 22, 2026
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NEWS
Meet our team at AACR Booth #3444 and explore our advanced multiomics solutions.
April 10, 2025
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Press Release
Signios Bio Launches with AI-Driven Bioinformatics Platform and Multiomics Expertise to Advance Precision Medicine
April 10, 2025
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NEWS
Global Health Council recognizes Signios Bio as a Health Hero in docuseries by same name
Ready to Start Your Sequencing Project?
Partner with a scientist-led team delivering genomics, single-cell, spatial, and proteomics services with integrated bioinformatics support.