Documents
Decoding lung cancer complexity with spatial transcriptomics
Lung cancer remains the leading cause of cancer-related mortality worldwide. Genetic alterations such as KRAS mutations, EGFR mutation, overexpression, and TP53 mutations are well-known drivers of tumorigenesis in lung cancer.
Advancing hematologic malignancy research with integrated multiomic solutions from Signios Bio
Hematologic malignancies often exhibit intricate clonal evolution, dynamic immune microenvironments within the bone marrow and periphery, and rare cell populations critical for disease progression and relapse.
Advancing oncology research with comprehensive immunoprofiling solutions from Signios Bio
Understanding the complex interplay between the immune system and cancer is crucial for developing effective therapies, particularly immune checkpoint inhibitors (ICIs). However, predicting patient response and deciphering resistance mechanisms remain significant challenges.
Characterizing solid tumor heterogeneity with multiomic approaches from Signios Bio
Solid tumors present immense complexity, characterized by significant intra-tumoral heterogeneity (ITH) arising from genetic, epigenetic, and transcriptional diversity.
Spatial Transcriptomics Brochure
Spatial Transcriptomics with Signiosbio: Where gene expression meets precision
Single-Cell Sequencing Solutions Whitepaper
Multiome insights, simplified: single-cell omics solutions for diverse sample types
Targeted genome editing in tomato: Unraveling gene regulation in carotenoid biosynthesis
Signios Bio leveraged its expertise in plant genomics to conduct a proof of concept study on carotenoid biosynthesis in tomatoes using CRISPR/Cas9 technology, published in Plant Cell Reports
Genomic insights into invasive rodent populations: unlocking conservation and synthetic gene drive potential
Signios Bio supported this research by providing high-quality genomic sequencing services, enabling the generation of detailed genetic data critical for understanding population dynamics and informing innovative conservation strategies
Unlocking Biological Insights with Signios Bio’s Advanced Multiomics Solutions
By integrating multiple modalities with our advanced bioinformatics tools and pipelines, we provide customized solutions tailored to your unique research needs.
Signios Bio Bioinformatics Services
Advancing omics research with comprehensive solutions and in-depth data analysis